FAM96B is a component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 and MMS19, FAM96B binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3D0].
cytosolic iron-sulfur assembly component 2B•
family with sequence similarity 96 member B•
mitotic spindle-associated MMXD complex subunit MIP18•
MSS19-interacting protein of 18 kDa•