CD96 is an immunoglobulin superfamily member involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. CD96 promotes NK cell-target cell adhesion by interacting with PVR present on target cells. CD96 may function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P40200].
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CD antigen CD96•
cell surface antigen CD96•
T cell activation, increased late expression•
t cell-activated increased late expression protein•
TACTILE•
T-cell surface protein tactile•