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CD25/IL-2R alpha Antibody

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. The IL2 receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [taken from NCBI Entrez Gene (Gene ID: 3559)].
IL2RA
interleukin 2 receptor subunit alpha
Interleukin-2 receptor subunit alpha
:  CD antigen CD25 CD25 IDDM10 IL-2 receptor subunit alpha IL2R IL-2R subunit alpha IL-2-RA IL2-RA IMD41 interleukin 2 receptor, alpha interleukin-2 receptor subunit alpha p55 TAC antigen TCGFR
Product
Specifications
Ordering Information
Human
WB, IP, ICC
residues 22-213 (ECD)
$389
$103
Human
IHC, ICC
between 222 and 272 (C-term)
$389
$103