Bethyl is now a part of Fortis Life Sciences. Learn more.

CD11b Antibody

CD11b is the most commonly used name for Integrin alpha M (ITGAM). Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAM combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). ITGAM/ITGB2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. [taken from NCBI Entrez Gene (Gene ID: 3684)].
integrin subunit alpha M
Integrin alpha-M
:  antigen CD11b (p170) CD antigen CD11b CD11 antigen-like family member B CD11B cell surface glycoprotein MAC-1 subunit alpha complement component 3 receptor 3 subunit CR-3 alpha chain CR3A integrin alpha-M integrin, alpha M (complement component 3 receptor 3 subunit) leukocyte adhesion receptor MO1 MAC-1 MAC1A macrophage antigen alpha polypeptide MO1A Neutrophil adherence receptor neutrophil adherence receptor alpha-M subunit SLEB6 More... Less...
Ordering Information
residues 17-334 (ECD)