Arginase 1 Antibody

Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P05089].
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ARG1
arginase 1
Arginase-1
:  arginase, liver liver-type arginase type I arginase
Product
Specifications
Ordering Information
Human
WB, IP, IHC, ICC
between 280 and 322 (C-term)
$360
$99