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4-1BBL/CD137L/TNFSF9 Antibody

4-1BBL (aka CD137L or TNFSF9) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. 4-1BBL and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells; they are also involved in promoting T lymphocyte proliferation. 4-1BBL has been shown to be required for the optimal CD8 responses in CD8 T cells. 4-1BBL is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [taken from NCBI Entrez Gene (Gene ID: 8744)].
TNF superfamily member 9
Tumor necrosis factor ligand superfamily member 9
:  4-1BB ligand 4-1BBL 4-1BB-L CD137L homolog of mouse 4-1BB-L receptor 4-1BB ligand TNLG5A tumor necrosis factor (ligand) superfamily, member 9 tumor necrosis factor ligand 5A tumor necrosis factor ligand superfamily member 9 tumor necrosis factor superfamily member 9 More... Less...
Ordering Information
residues 71-254 (ECD)