Due to inventory, no orders will be processed and shipped on Thursday, September 21 and Friday, September 22.
All orders placed on these days will be processed and shipped overnight for delivery on Tuesday, September 26.

PBRM1 Rabbit Monoclonal, Antibody

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PBRM1 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PBRM1 has been proposed to function as a tumor suppressor protein. Recently, PBRM1 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21.
PBRM1
polybromo 1
Protein polybromo-1
:  BAF180 BRG1-associated factor 180 hPB1 PB1 polybromo-1D
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P, ICC
$229
$99
Human
IP
Between 1 and 50
$339
$99
Human, Mouse
WB, IP, IHC-P
Between 1639 and 1689
$339
$229
$99
Human, Mouse
Includes: 1 each of A301-590A and A301-591A
$472
Includes: 1 each of A301-590A and A301-591A