Due to inventory, Bethyl will be closed on Thursday, September 21 and Friday, September 22.
All orders placed on these days will be processed and shipped overnight for delivery on Tuesday, September 26.

LARG Antibody

LARG (leukemia-associated RhoGEF) is homologous to PDZ-RhoGEF and functions as a RhoA-specific guanine nucleotide exchange factor. RhoGEFs catalyze the exchange of GDP for GTP on the GTPase, Rho, to activate downstream signaling pathways. LARG contains a PDZ [post synaptic density protein (PSD95), Drosophila discs-large tumor suppressor (DIgA), and zonula occludens-1 protein (zo-1)] domain which is an 80-90 amino acid structural domain found in signaling proteins in bacteria, yeast, plants, and animals. LARG is proposed to play a role in cell polarity and microtubule dynamics and may act as a GTPase-activating protein (GAP) for the heterotrimeric Galpha(12) and Galpha(13) proteins.
ARHGEF12
Rho guanine nucleotide exchange factor 12
Rho guanine nucleotide exchange factor 12
:  KIAA0382 LARG leukemia-associated rho guanine nucleotide exchange factor leukemia-associated RhoGEF PRO2792 Rho guanine nucleotide exchange factor (GEF) 12
Product
Specifications
Ordering Information
Human
WB
Between 1350 and 1400
$339
$229
$99
Human
WB, IP
Between 1494 and 1544
$339
$229
$99
Human
Includes: 1 each of A301-959A and A301-960A
$472
Includes: 1 each of A301-959A and A301-960A