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CIP2A Antibody

CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.
CIP2A
cell proliferation regulating inhibitor of protein phosphatase 2A
Protein CIP2A
:  cancerous inhibitor of PP2A cancerous inhibitor of protein phosphatase 2A KIAA1524 p90 p90 autoantigen protein CIP2A
Product
Specifications
Ordering Information
Human
IP, IHC
Between 550 and 600
$339
$99
Human, Mouse, Rat
WB, IP, IHC
Between 853 and 903
$339
$229
$99
Human, Mouse, Rat
WB, IP, IHC
Includes: 1 each of A301-453A and A301-454A
$472
Includes: 1 each of A301-453A and A301-454A
Human
IHC, IHC-IF
Between 550 and 600
$360
$99
Human, Mouse
WB, IP
Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein
$229
$99