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Aly Antibody

Aly (ally of AML-1 and LEF-1) is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. Aly also functions as a chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation. Additionally, Aly plays a role in mRNA processing and export and may function as scaffold that mediates interactions between proteins and/or RNA. Aly is also part of the exon junction complex that remains associated with spliced mRNA and plays an important role in mRNA export and nonsense-mediated RNA decay. Aly directs mRNA derived from Herpes simplex virus intron-less genes to the NXF1-mediated export pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q886V81].
ALYREF
Aly/REF export factor
THO complex subunit 4
:  ally of AML-1 and LEF-1 ALY ALY/REF Aly/REF export factor BEF bZIP enhancing factor bZIP-enhancing factor BEF REF THO complex 4 tho4 THOC4 transcriptional coactivator Aly/REF
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P
Between 25 and 75
100
$339
$229
$99
Human
IP, IHC-P
Between 75 and 125
100
$339
$99
Human
100
Includes: 1 each of A302-892A and A302-893A
$472
Includes: 1 each of A302-892A and A302-893A