Come Visit Us at AACR! Booth #2141.

ASXL2 Antibody

The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).
ASXL2
ASXL transcriptional regulator 2
Putative Polycomb group protein ASXL2
:  additional sex combs like 2, transcriptional regulator additional sex combs-like protein 2 ASXH2 polycomb group protein ASXH2 putative Polycomb group protein ASXL2 SHAPNS
Product
Specifications
Ordering Information
Human
WB, IP
Between 600 and 650
$339
$229
$99