AKAP8L/HA95 Antibody

AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington’s disease.
AKAP8L
A-kinase anchoring protein 8 like
A-kinase anchor protein 8-like
:  A kinase (PRKA) anchor protein 8-like AKAP8-like protein HA95 HAP95 Helicase A-binding protein 95 helicase A-binding protein 95 kDa homologous to AKAP95 protein NAKAP NAKAP95 neighbor of A kinase anchoring protein 95 neighbor of AKAP95 neighbor of A-kinase anchoring protein 95 Neighbor of A-kinase-anchoring protein 95 testis tissue sperm-binding protein Li 90mP More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 525 and 575
$339
$229
$99
Human
WB, IP, IHC-P
Between 596 and 646
$339
$229
$99
Human
WB, IP, IHC-P
Includes: 1 each of A301-365A and A301-366A
$472
Includes: 1 each of A301-365A and A301-366A
Human
IHC-P, IF
Between 596 and 646
$360
$99