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ACC1/ACC-alpha Antibody

ACC1/ACC-alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA in the enzymatic pathway of long-chain fatty-acid synthesis. ACC1/ACC-alpha has been identified as a partner of BRCA1. Through this interaction, ACC1/ACC-alpha may contribute to the tumor suppressor activity of BRCA1 as demonstrated by the finding that disruption of this interaction increases lipid synthesis in mammary epithelial cells. In this context, lipogenesis has been closely linked to tumorigenesis and ACC1/ACC-alpha has been found to be highly expressed in human breast carcinomas.
ACACA
acetyl-CoA carboxylase alpha
Acetyl-CoA carboxylase 1
:  ACAC ACACAD ACC ACC1 ACCA ACC-alpha acetyl-CoA carboxylase 1 acetyl-Coenzyme A carboxylase alpha Biotin carboxylase
Product
Specifications
Ordering Information
Human
IP
Between 1925 and 1975
100
$339
$99
Human
WB
Between 2333 and C-term
100
$339
$229
$99
Human
100
Includes: 1 each of A300-986A and A300-987A
$472
Includes: 1 each of A300-986A and A300-987A