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AATF/Che-1 Antibody

AATF/Che-1 was identified as a protein that interacts with RNA polymerase II and is involved in the regulation of gene transcription and cell proliferation. AATF/Che-1 has been demonstrated to promote cell proliferation by acting as a competitor of histone deacetylase 1 (HDAC1) and interfering with HDAC1’s interaction with the growth inhibiting protein pRB. AATF has also been shown to function as a nuclear receptor coactivator and a repressor of apoptosis.
AATF
apoptosis antagonizing transcription factor
Protein AATF
:  apoptosis-antagonizing transcription factor BFR2 CHE1 CHE-1 DED rb-binding protein Che-1
Product
Specifications
Ordering Information
Human
WB, IP, PLA
Between 125 and 175
$339
$229
$99
Human
IP
Between 510 and C-term
$339
$99
Human
Includes: 1 each of A301-031A and A301-032A
$472
Includes: 1 each of A301-031A and A301-032A