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STUB1/CHIP Antibody

STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimers and Down’s syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53.
STIP1 homology and U-box containing protein 1
E3 ubiquitin-protein ligase CHIP
:  antigen NY-CO-7 carboxy terminus of Hsp70-interacting protein CHIP CLL-associated antigen KW-8 E3 ubiquitin-protein ligase CHIP heat shock protein A binding protein 2 (c-terminal) HSPABP2 NY-CO-7 RING-type E3 ubiquitin transferase CHIP SCAR16 SDCCAG7 serologically defined colon cancer antigen 7 STIP1 homology and U box-containing protein 1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase UBOX1 More... Less...
Ordering Information
Human, Mouse
between 1 and 50
between 253 and 303
Human, Mouse
Between 253 and 303