RPA70 Antibody

Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.
replication protein A1
Replication protein A 70 kDa DNA-binding subunit
:  HSSB MST075 MSTP075 REPA1 replication factor A protein 1 replication protein A 70 kDa DNA-binding subunit replication protein A1, 70kDa RF-A RF-A protein 1 RP-A RP-A p70 RPA70 single-stranded DNA-binding protein
Ordering Information
Human, Mouse
between 350 and 400
Human, Mouse
Between 350 and 400