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PHD4 Antibody

PHD4 is one of 4 PHD (PHD1-4) enzymes that function as oxygen sensors and are responsible for the post-translational modification of HIF-1alpha, a component of a transcriptional complex involved in oxygen homeostasis. During normoxic levels, PHDs catalyze the hydroxylation of prolyl residues on HIF-1alpha and target it for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. The PHD isoforms appear to function in a non-redundant manner and may differ in their expression patterns and their catalytic selectivity.
P4HTM
prolyl 4-hydroxylase, transmembrane
Transmembrane prolyl 4-hydroxylase
:  EGLN4 HIFPH4 HIF-PH4 HIF-prolyl hydroxylase 4 HPH-4 hypoxia-inducible factor prolyl 4-hydroxylase hypoxia-inducible factor prolyl hydroxylase 4 P4H with transmembrane domain P4H-TM PH4 PH-4 PHD4 proline 4-hydroxylase prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) Prolyl hydroxlase domain-containing 4 transmembrane prolyl 4-hydroxylase More... Less...
Product
Specifications
Ordering Information
Human
WB
between 450 and C-term
$339
$229
$99