Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
MPRIP targets myosin phosphatase to the actin cytoskeleton. It is required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MPRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6WCQ1].