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HIF2-alpha Antibody

The gene EPAS1 encodes for the transcription factor endothelial PAS domain-containing protein 1, and is induced as oxygen levels fall. Commonly called hypoxia inducible factor 2A (HIF2a), this protein is involved in the induction of oxygen regulated genes, binding to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. An important cancer biomarker, HIF2a may also play a role in Tibetan high-altitude adaptation (Am J Hum Genet. 2015 Jul 2; 97(1): 54–66.) and mutations in the EPAS1 gene are associated with erythrocytosis familial type 4 [taken from NCBI Entrez Gene (Gene ID: 2034) and UniProtKB (Entry: Q99814)].
endothelial PAS domain protein 1
Endothelial PAS domain-containing protein 1
:  basic-helix-loop-helix-PAS protein MOP2 bHLHe73 class E basic helix-loop-helix protein 73 ECYT4 EPAS-1 HIF-1 alpha-like factor HIF-1-alpha-like factor HIF-1alpha-like factor HIF2A HIF-2-alpha HIF2-alpha HLF hypoxia-inducible factor 2 alpha hypoxia-inducible factor 2-alpha member of PAS protein 2 MOP2 PAS domain-containing protein 2 PASD2 More... Less...
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