FKBP5/FKBP51 Antibody

FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.
FKBP5
FK506 binding protein 5
Peptidyl-prolyl cis-trans isomerase FKBP5
:  51 kDa FK506-binding protein 51 kDa FKBP 54 kDa progesterone receptor-associated immunophilin AIG6 androgen-regulated protein 6 FF1 antigen FK506-binding protein 5 FKBP-5 FKBP51 FKBP-51 FKBP54 HSP90-binding immunophilin P54 peptidylprolyl cis-trans isomerase PPIase PPIase FKBP5 Ptg-10 rotamase T-cell FK506-binding protein More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 225 and 275
$339
$99
Human
WB, IP, IHC
Between 407 and 457
$339
$229
$99
Human
WB, IP, IHC
Includes: 1 each of A301-429A and A301-430A
$472
Includes: 1 each of A301-429A and A301-430A
Human
IHC
Between 407 and 457
$360
$99