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FBW7 Antibody

FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis.
FBXW7
F-box and WD repeat domain containing 7
F-box/WD repeat-containing protein 7
:  AGO archipelago Archipelago homolog CDC4 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila) F-box and WD-40 domain-containing protein 7 F-box protein FBW7 F-box protein FBX30 F-box protein SEL-10 F-box/WD repeat-containing protein 7 FBW6 FBW7 FBX30 FBXO30 FBXW6 hAgo hCdc4 homolog of C elegans sel-10 SEL10 SEL-10 More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 1 and 50
$350
$99
Human
IP, IHC
between 50 and 100
$350
$99
Human
IHC
Between 50 and 100
$371
$99