DDX5 Antibody

DDX5 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX5 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX5 has also been found to interact with CBP/300, Smad3, and p53 to modulate transcription. DDX5 is closely related to and forms heterodimers with DDX17.
DDX5
DEAD-box helicase 5
Probable ATP-dependent RNA helicase DDX5
:  ATP-dependent RNA helicase DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 DEAD box protein 5 DEAD box-5 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD) G17P1 HLR1 HUMP68 p68 RNA helicase p68
Product
Specifications
Ordering Information
Human
WB, IP
Between 550 and 600
$339
$229
$99
Human, Mouse
WB, IP, IHC
Between 575 and C-term
$339
$229
$99
Human, Mouse
WB, IP, IHC
Includes: 1 each of A300-522A and A300-523A
$472
Includes: 1 each of A300-522A and A300-523A
Human, Mouse
IHC
Between 575 and C-term
$360
$99