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COP1/RFWD2 Antibody

Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.
COP1, E3 ubiquitin ligase
E3 ubiquitin-protein ligase RFWD2
:  constitutive photomorphogenesis protein 1 homolog constitutive photomorphogenic protein 1 E3 ubiquitin-protein ligase COP1 E3 ubiquitin-protein ligase RFWD2 hCOP1 putative ubiquitin ligase COP1 RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase RING finger and WD repeat domain protein 2 RING finger protein 200 RING-type E3 ubiquitin transferase RFWD2 RNF200 More... Less...
Ordering Information
Human, Mouse
Between 1 and 50
between 100 and 150