Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
AktS1/PRAS40 interacts with raptor as a component of the mammalian target of rapamycin complex 1 (mTORC1). One study suggests that AktS1/PRAS40 may function to regulate mTORC1 kinase activity by inhibiting substrate binding. Another study suggests that AktS1/PRAS40 functions downstream of mTORC1 and upstream from its effectors S6K1, and 4E-BP1.