UPF3B Antibody

UPF3B (UPF regulator of nonsense transcripts homolog B) is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. UPF3B recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2, UPF3B stimulates both ATPase and RNA helicase activities of UPF1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BZI7].
UPF3B
UPF3 regulator of nonsense transcripts homolog B (yeast)
Regulator of nonsense transcripts 3B
:  HUPF3B hUpf3p-X mental retardation, X-linked 62 MRX62 MRXS14 nonsense mRNA reducing factor 3B RENT3B UPF3B pseudogene 1 UPF3B pseudogene 2 UPF3B pseudogene 3 UPF3BP1 UPF3BP2 UPF3BP3 Upf3p-X UPF3X up-frameshift suppressor 3 homolog B up-frameshift suppressor 3 homolog on chromosome X More... Less...
Product
Specifications
Ordering Information
Human
WB, IP
Between 300 and 350
$339
$229
$99
Human
IP
Between 433 and 483
$339
$99
Human
WB, IP
Includes: 1 each of A303-688A and A303-689A
$472
Includes: 1 each of A303-688A and A303-689A