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Sprouty 2 Antibody

Sprouty 2 contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells sprouty 2 is transiently upregulated in response to fibroblast growth factor two. Sprouty 2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. Sprouty 2 interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. Sprouty 2 may play a role in alveoli branching during lung development as shown by a similar mouse protein [taken from NCBI Entrez Gene (Gene ID: 10253)].
SPRY2
sprouty RTK signaling antagonist 2
Protein sprouty homolog 2
:  hSPRY2 IGAN3 protein sprouty homolog 2 Spry-2
Product
Specifications
Ordering Information
Human
IP
between 75 and 125
$339
$99
Human
IP
between 265 and 315
$339
$99
Human
IP
Includes: 1 each of A303-534A and A303-535A
$472