TRAF2 Antibody

TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. TRAF2 is required for normal antibody isotype switching from IgM to IgG. TRAF2 has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. TRAF2 is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q12933].
TRAF2
TNF receptor associated factor 2
TNF receptor-associated factor 2
:  E3 ubiquitin-protein ligase TRAF2 MGC:45012 TRAP TRAP3 tumor necrosis factor type 2 receptor associated protein 3 tumor necrosis factor type 2 receptor-associated protein 3
Product
Specifications
Ordering Information
Human
WB, IP
Between 175 and 225
$339
$229
$99
Human
IP, IHC
Between 300 and 350
$339
$99
Human
WB, IP, IHC
Includes: 1 each of A303-460A and A303-461A
$472
Includes: 1 each of A303-460A and A303-461A