Thymocyte-expressed molecule involved in selection (THEMIS) plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells [taken from NCBI Entrez Gene (Gene ID: 387357)].
signaling phosphoprotein specific for T cells•
thymocyte selection pathway associated•
thymocyte-expressed molecule involved in selection•