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SOS2 Antibody

SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.
SOS Ras/Rho guanine nucleotide exchange factor 2
Son of sevenless homolog 2
:  guanine nucleotide releasing factor NS9 son of sevenless homolog 2 SOS-2
Ordering Information
Human, Mouse
between 1282 and 1332