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RIP3 Antibody

Receptor-interacting serine/threonine-protein kinase 3 (RIP3) is essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIP3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIP3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production [taken from the Universal Protein Resource (UniProt)].
receptor interacting serine/threonine kinase 3
Receptor-interacting serine/threonine-protein kinase 3
:  receptor interacting protein 3 Receptor-interacting protein 3 receptor-interacting serine/threonine-protein kinase 3 RIP3 RIP-3 RIP-like protein kinase 3
Ordering Information
Between 400 and 450