RAN Antibody

RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor [taken from NCBI Entrez Gene (Gene ID: 5901)].
RAN
RAN, member RAS oncogene family
GTP-binding nuclear protein Ran
:  androgen receptor-associated protein 24 ARA24 Gsp1 GTPase Ran guanosine triphosphatase Ran member RAS oncogene family OK/SW-cl.81 RanGTPase ras-like protein TC4 ras-related nuclear protein TC4
Product
Specifications
Ordering Information
Human, Mouse
WB, IP, IHC
Between 175 to 225
$339
$229
$99
Human, Mouse
WB, IP, IHC
Between 166 to 216
$339
$229
$99
Human, Mouse
WB, IP, IHC
Includes: 1 each of A304-297A and A304-298A
$472
Includes: 1 each of A304-297A and A304-298A