Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
Par4 (prostate apoptosis response-4) was identified in a differential screen for pro-apoptotic genes in a prostate carcinoma cell line. Par4 activates apoptosis via the Fas prodeath pathway and by inhibition of NF-kappa-B transcriptional activity. Par4 may be a tumor suppressor. It has been shown to interact with a wide variety of proteins including atypical PKCs, and the Wilms’ tumor suppressor.