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MCAK Antibody

Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.
KIF2C
kinesin family member 2C
Kinesin-like protein KIF2C
Product
Specifications
Ordering Information
Human
IP, IHC
between 50 and 100
$339
$99
Human
WB, IP
between 550 and 600
$339
$229
$99
Human
WB, IP
between 675 and C-term
$339
$229
$99
Mouse
WB, IP, IHC
between 50 and 100
$339
$229
$99
Mouse
IP
between 550 and 600
$339
$99
Human
WB, IP, IHC
Includes: 1 each of A300-806A, A300-807A and A300-808A
$707
Mouse
WB, IP, IHC
Includes: 1 each of A300-921A and A300-922A
$472
Human
IHC
Between 50 and 100
$360
$99
Mouse
IHC
Between 50 and 100
$360
$99