Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
TPX2 is a microtubule associated protein (MAP) that co-localizes with spindle microtubules during M-phase of the cell cycle. It may function to nucleate microtubules and initiate microtubule polymerization and assembly for spindle formation. TPX2 is a target of RanGTP, a small GTPase that coordinates spindle assembly. TPX2 protein levels peak during mitosis and are tightly regulated by ubiquitination during the cell cycle.