RCC2 Antibody

RCC2 (regulator of chromosome condensation 2) is a member of the RCC1 family of guanine nucleotide exchange factors. RCC2 has been identified as part of the chromosomal passenger complex (CPC) which coordinates the chromosomal and cytoskeletal events of mitosis. Chromosomal passengers are proteins present in complexes with aurora B, inner centromeric protein (INCENP), survivin, and borealin. RCC2 has been demonstrated to be required for the recruitment of survivin and aurora B and is essential for proper chromosome segregation and the completion of cell cleavage. Loss of RCC2 inhibits spindle assembly, activates the spindle assembly checkpoint, and blocks cells in prometaphase.
RCC2
regulator of chromosome condensation 2
Protein RCC2
:  RCC1-like protein TD-60 TD-60 telophase disk protein of 60 kDa
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 1 and 50
$339
$229
$99
Human, Mouse
WB, IHC
Between 475 and C-term
$339
$229
$99
Human, Mouse
WB, IP, IHC
Includes: 1 each of A300-872A and A300-873A
$472
Includes: 1 each of A300-872A and A300-873A
Human, Mouse
IHC
Between 475 and C-term
$360
$99