KIF20B Antibody

Kinesin family member 20B (KIF20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). KIF20B is required for proper midbody organization and abscission in polarized cortical stem cells. It plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. KIF20B participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, KIF20B cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. It is involved in cerebral cortex growth (By similarity). KIF20B acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [taken from the Universal Protein Resource (UniProt)].
kinesin family member 20B
Kinesin-like protein KIF20B
:  cancer/testis antigen 90 CT90 Kinesin family member 20B kinesin-like protein KIF20B kinesin-related motor interacting with PIN1 KRMP1 mitotic kinesin-like protein mitotic kinesin-related protein M-phase phosphoprotein 1 MPHOSPH1 MPP1 MPP-1
Ordering Information
Between 825 and 875