TLK1 Antibody

Tousled-like kinase 1 (TLK1) is a serine/threonine kinase involved in chromatin assembly and the DNA damage response. The tousled (Tsl) kinase was first identified in Arabidopsis thaliana and speculated to be involved in cell division during patterning of plant organs. There are two tousled-like kinases in humans, TLK1 and TLK2, that can dimerize or heterodimerize for function and can be phosphorylated and inactivated by Chk1 in response to DNA damage. The histone chaperone, Asf1 (anti-silencing function 1), has been reported as a substrate for both TLK1 and TLK2. TLK1 has also been shown to be important for cell cycle progression and proper chromosome segregation.
TLK1
tousled like kinase 1
Serine/threonine-protein kinase tousled-like 1
:  KIAA0137 PKU-BETA serine threonine protein kinase SNARE protein kinase SNAK tousled-like kinase 1
Product
Specifications
Ordering Information
Human, Mouse
WB, IP, PLA
Between 150 and 200
$339
$229
$99
Human, Mouse
WB, IP
Between 716 and 766
$339
$229
$99
Human, Mouse
WB, IP, PLA
Includes: 1 each of A301-252A and A301-253A
$472
Includes: 1 each of A301-252A and A301-253A