PSMD2 Antibody

PSMD2 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 2] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD2 is a subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5708)].
proteasome 26S subunit, non-ATPase 2
26S proteasome non-ATPase regulatory subunit 2
:  26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit RPN1 26S proteasome regulatory subunit S2 26S proteasome subunit p97 55.11 protein P97 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 protein 55.11 RPN1 S2 TNFR-associated protein 2 TRAP2 tumor necrosis factor type 1 receptor-associated protein 2 More... Less...
Ordering Information
Between 1 and 50
Human, Mouse
Between 50 and 100