SEMA4D Antibody

Sema4D (Semaphorin-4D) is a cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Sema4D promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Sema4D regulates dendrite and axon branching and morphogenesis. It promotes the migration of cerebellar granule cells and of endothelial cells. In the immune system Sema4D induces B-cells to aggregate and improves their viability (in vitro). Sema4D also promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92854].
SEMA4D
semaphorin 4D
Semaphorin-4D
:  A8 BB18 C9orf164 CD antigen CD100 CD100 chromosome 9 open reading frame 164 coll-4 FLJ39737 GR3 M-sema G M-sema-G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D SEMAJ More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 800 to 850
$339
$99
Human
WB, IP
Between 812 to 862
$339
$229
$99
Human
WB, IP
Includes: 1 each of A304-394A and A304-395A
$472
Includes: 1 each of A304-394A and A304-395A