mTOR Antibody

Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt.
MTOR
mechanistic target of rapamycin kinase
Serine/threonine-protein kinase mTOR
:  FK506 binding protein 12-rapamycin associated protein 2 FK506-binding protein 12-rapamycin complex-associated protein 1 FKBP12-rapamycin complex-associated protein FKBP12-rapamycin complex-associated protein 1 FKBP-rapamycin associated protein FRAP FRAP1 FRAP2 mammalian target of rapamycin Mechanistic target of rapamycin mechanistic target of rapamycin (serine/threonine kinase) mTOR RAFT1 rapamycin and FKBP12 target 1 rapamycin associated protein FRAP2 rapamycin target protein 1 RAPT1 serine/threonine-protein kinase mTOR SKS More... Less...
Product
Specifications
Ordering Information
Human
WB, IP, ICC
between 200 and 250
$339
$229
$99
Human
WB, IP
between 200 and 250
$339
$229
$99
Human, Mouse
WB, IP
between 1350 and 1400
$339
$229
$99
Human
WB, IP
between 1675 and 1725
$339
$229
$99
Human, Mouse
WB, IP, ICC
Includes: 1 each of A300-503A and A300-504A
$472
Human, Mouse
WB, IP
Includes: 1 each of A301-143A and A301-144A
$472