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PTPN6/SHP1 Antibody

PTPN6/SHP-1 modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, SHP-1 induces UBE2V2 expression upon angiotensin II stimulation.SHP-1 plays a key role in hematopoiesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P29350].
protein tyrosine phosphatase, non-receptor type 6
Tyrosine-protein phosphatase non-receptor type 6
:  HCP HCPH hematopoietic cell phosphatase hematopoietic cell protein-tyrosine phosphatase HPTP1C protein-tyrosine phosphatase 1C protein-tyrosine phosphatase SHP-1 PTP-1C SHP1 SHP-1 SHP-1L SH-PTP1 tyrosine-protein phosphatase non-receptor type 6
Ordering Information
Between 545 and 595