NUMB Antibody

NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.
NUMB
NUMB, endocytic adaptor protein
Protein numb homolog
:  c14_5527 C14orf41 chromosome 14 open reading frame 41 h-Numb numb (Drosophila) homolog numb homolog Protein S171 S171
Product
Specifications
Ordering Information
Human
WB, IP
Between 375 and 425
$339
$229
$99
Human
IP
Between 525 and 575
$339
$99
Human
WB, IP
Includes: 1 each of A301-714A and A301-715A
$472
Includes: 1 each of A301-714A and A301-715A