Topo II Alpha Antibody

Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
TOP2A
topoisomerase (DNA) II alpha
DNA topoisomerase 2-alpha
:  DNA gyrase DNA topoisomerase (ATP-hydrolyzing) DNA topoisomerase II, 170 kD DNA topoisomerase II, alpha isozyme TOP2 topoisomerase (DNA) II alpha 170kDa TP2A
Product
Specifications
Ordering Information
Human
WB, IP, IHC
Between 1500 and C-term
$339
Human
IHC
Between 1500 and C-term
$360
$99