PKM2 Antibody

Pyruvate Kinase M2 (PKM2) is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. PKM2 also stimulates POU5F1-mediated transcriptional activation, and plays a general role in caspase independent cell death of tumor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P14618].
PKM
pyruvate kinase, muscle
Pyruvate kinase PKM
:  CTHBP cytosolic thyroid hormone-binding protein epididymis secretory protein Li 30 HEL-S-30 OIP3 OIP-3 OPA-interacting protein 3 p58 PK, muscle type PK3 PKM2 pyruvate kinase 2/3 pyruvate kinase isozymes M1/M2 pyruvate kinase muscle isozyme TCB THBP1 thyroid hormone-binding protein 1 thyroid hormone-binding protein, cytosolic tumor M2-PK More... Less...
Product
Specifications
Ordering Information
Human
WB, IP, IHC
Between 1 and 50
$339
$229
$99
Human, Mouse
WB, IP, IHC, PLA
Between 481 and 531
$339
$229
$99
Human, Mouse
WB, IP, IHC, PLA
Includes: 1 each of A303-659A and A303-660A
$472
Includes: 1 each of A303-659A and A303-660A