JMJD2C Antibody

JMJD2C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2C, also known as GASC1 (gene amplified in squamous cell carcinoma), has been found to be amplified in several esophageal squamous carcinomas and inhibition of JMJD2C/GASC1 expression results in decreased cellular proliferation.
lysine demethylase 4C
Lysine-specific demethylase 4C
:  GASC1 GASC-1 protein gene amplified in squamous cell carcinoma 1 protein JHDM3C JmjC domain-containing histone demethylation protein 3C JMJD2C jumonji domain containing 2C jumonji domain-containing protein 2C KIAA0780 lysine (K)-specific demethylase 4C TDRD14C tudor domain containing 14C More... Less...
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