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Goat anti-HIF1-alpha Antibody
Bethyl Laboratories® Catalog # A303-907A-T A303-907A

Validated

Goat anti-HIF1-alpha Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (3)

Target: HIF1-alpha

Reactivity: Human

Applications:

Host: Goat

Clonality: Polyclonal

Conjugate:

Purity:

1 Figure

parentCodeBETHYL-A303-907

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For ordering information, see our International Distributors

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Product has been discontinued
Rabbit anti-HIF1-alpha Antibody
Bethyl Laboratories® Catalog # A300-286A A300-286A-T

Validated

Rabbit anti-HIF1-alpha Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (9) Citations ()

Target: HIF1-alpha

Reactivity: Human, Mouse

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

5 Figures

parentCodeBETHYL-A300-286

Bulk Request

For ordering information, see our International Distributors

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Product has been discontinued
Rabbit anti-HIF1-alpha IHC Antibody
Bethyl Laboratories® Catalog # IHC-00460 IHC-00460-T

Validated

Rabbit anti-HIF1-alpha IHC Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (7) Citations ()

Target: HIF1-alpha

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

2 Figures

parentCodeBETHYL-IHC-00460

Bulk Request

For ordering information, see our International Distributors

Distributors

Product has been discontinued
Rabbit anti-HIF1-alpha Recombinant Monoclonal Antibody [BL-124-3F7]
Bethyl Laboratories® Catalog # A700-001-T A700-001 A700-001CF

Validated

Rabbit anti-HIF1-alpha Recombinant Monoclonal Antibody [BL-124-3F7]

Validation Performed

Pillar 1: Independent Antibodies
Pillar 2: Complementary Assays
Pillar 5: Protein OE/Epitope Tags

Learn more about the validation performed

Documents (9) Citations ()

Target: HIF1-alpha

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Recombinant Monoclonal

Conjugate:

Purity:

5 Figures

parentCodeBETHYL-A700-001

Bulk Request

For ordering information, see our International Distributors

Distributors

Product has been discontinued

Hypoxia Signaling: HIF1-alpha & HIF2-alpha Recombinant Rabbit Monoclonal Antibodies
Article

The hypoxic response pathway is triggered by low levels of oxygen in the cellular environment. Hypoxia inducible transcription factor (HIF) is central to the hypoxic response. HIF exists as a heterodimeric transcription factor composed of an alpha and beta subunit. In mammals there are three HIF-alpha subunits, HIF1-alpha, HIF2-alpha, and HIF3-alpha, and one beta subunit, the aryl hydrocarbon receptor nuclear translocator (ARNT). The overexpression of HIF1-alpha and HIF2-alpha is associated with poor survival rates for various cancers. Experimental and clinical evidence strongly suggests HIF1-alpha and HIF2-alpha influence tumor development and response to treatment. Because of this, there has been major interest in developing selective HIF inhibitors; but due to the complexity of the HIF pathway, the process has been challenging. Thus, future work for therapeutic targeting of the HIFs will require a better understanding of both the HIF1-alpha and HIF2-alpha pathways.

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