Due to the holidays, Bethyl will close at noon on December 22nd and reopen January 2, 2018.
All orders placed after Thursday, December 21st will be processed and shipped overnight for delivery on Wednesday, January 3.

DFF45/DFFA Antibody

DNA fragmentation factor (DFF45/DFFA) is a component of DFF, the principle DNA endonuclease responsible for nucleosomal DNA cleavage during apoptosis. In the DFF complex, DFF45/DFFA heterodimerizes with DFF40 and is a substrate of the apoptotic effector, caspase 3. Initiation of the cellular apoptotic program results in the activation of caspase 3 and the cleavage and release of DFF45 from its heterodimeric partner, DFF40. The release of DFF40 from the inhibitory activity of DFF45 allows DFF40 to function as a DNA endonuclease to promote chromosomal DNA fragmentation. A 35 kDa splice variant of DFF45, DFF35, also exists and functions as a chaperone and alternative heterodimeric partner for DFF40.
DFFA
DNA fragmentation factor subunit alpha
DNA fragmentation factor subunit alpha
:  DFF1 DFF45 DFF-45 DNA fragmentation factor 45 kDa subunit DNA fragmentation factor, 45 kD, alpha polypeptide DNA fragmentation factor, 45 kD, alpha subunit DNA fragmentation factor, 45kDa, alpha polypeptide ICAD inhibitor of CAD
Product
Specifications
Ordering Information
Human
WB, IP, IHC
Between 271 and 331
$339
$229
$99
Human
IHC, IF
Between 271 and 331
$360
$99
Human
WB, IP, IHC
Includes: 1 each of A301-420A and A301-421A
$472
Includes: 1 each of A301-420A and A301-421A