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Rabbit anti-Caspase 3 Antibody
Bethyl Laboratories® Catalog # A303-657A-T A303-657A

Validated

Rabbit anti-Caspase 3 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (4) Citations ()

Target: Caspase 3

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

4 Figures

parentCodeBETHYL-A303-657

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Rabbit anti-CASP9/Caspase 9 Antibody
Bethyl Laboratories® Catalog # A305-252A-T A305-252A

Validated

Rabbit anti-CASP9/Caspase 9 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (3)

Target: CASP9/Caspase 9

Reactivity: Human, Mouse

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

1 Figure

parentCodeBETHYL-A305-252

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Human HDL-3
Bethyl Laboratories® Catalog # P81-130

Documents (3)

Target: HDL-3

Conjugate:

Purity:

parentCodeBETHYL-P81-130

$193.00

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Rabbit anti-14-3-3 theta Antibody
Bethyl Laboratories® Catalog # A303-146A-T A303-146A

Validated

Rabbit anti-14-3-3 theta Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (5) Citations ()

Target: 14-3-3 theta

Reactivity: Human, Mouse

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

3 Figures

parentCodeBETHYL-A303-146

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TIM-3 for a Change
Kimberly Holloway, Ph.D.

Article

The Resistance
Immune-checkpoint inhibitors is a popular topic of current discussion within the realm of tumor therapeutics. Most notably cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed death receptor 1 (PD-1) have garnered the most attention. The first immune checkpoint inhibitor associated with overall survival within a phase 3 metastatic melanoma study, Ipilimumab, is a fully humanized antibody against cytotoxic T-lymphocyte–associate-d antigen 4 (CTLA-4) antibody.^1,2 Blockade of PD-1 has achieved revolutionary clinical impact in many solid cancers; however, there has been certain roadblocks which have prevented full response to anti-PD-1 therapy.^3-5 A significant percentage of cancer patients fail to respond to these therapies due to compensatory immune inhibitory pathways.⁶

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The Resistance