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Caspase 3 Antibody

Caspase 3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 3 cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase 3 is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease [taken from NCBI Entrez Gene (Gene ID: 836)].
caspase 3
:  apopain CASP-3 caspase 3, apoptosis-related cysteine peptidase caspase 3, apoptosis-related cysteine protease caspase-3 CPP32 CPP-32 CPP32B cysteine protease CPP32 PARP cleavage protease procaspase3 protein Yama SCA-1 SREBP cleavage activity 1
Ordering Information
Between 1 and 50