Rabbit anti-SOS2 Antibody
Catalog #
SOS2
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1282 and 1332
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Human
2 - 8 °C
1 year from date of receipt
SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.
Alternate Names
guanine nucleotide releasing factor; NS9; son of sevenless homolog 2; SOS-2
Applications