/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-PRKAR2A/PKA-RIIalpha IHC Antibody
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Primary Antibodies  

Rabbit anti-PRKAR2A/PKA-RIIalpha IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PRKAR2A/PKA-RIIalpha

Reactivity:

Human

Applications:

IHC

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 50 and 100

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Monkey

Antigen Species

Human

Concentration
100 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

PRKAR2A/PKA-RIIalpha (cAMP-dependent protein kinase type II-alpha regulatory subunit) is one of 4 isoforms of regulatory subunits of the cAMP-dependent protein kinase (PKA). RI and RII are the two major classes of regulatory subunits. RI and RII each have an alpha and beta isoform. The regulatory subunits perform non-redundant functions as receptors for CAMP signals and for the differential regulation of PKA activity. The PRKAR2A/PKA-RIIalpha functions as an inhibitor of the PKA holoenzyme. PRKAR2A/PKA-RIIalpha subunits have been found to interact with A-kinase anchoring proteins (AKAPs), proteins that function to target the subcellular localization of PKA.

5576

PRKAR2A

protein kinase cAMP-dependent type II regulatory subunit alpha

P13861

cAMP-dependent protein kinase type II-alpha regulatory subunit

Alternate Names

cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; PKR2; PRKAR2; protein kinase A, RII-alpha subunit; protein kinase, cAMP-dependent, regulatory subunit type II alpha

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.